The Illinois International Stuttering Research Program

CURRICULUM VITAE(June, 2006)

Nancy J. Cox

The University of Chicago
Department of Medicine
Section of Genetic Medicine
5841 South Maryland Avenue
M265 ~ MC 6091
Chicago , IL 60637
Phone: (773) 834-1001
Fax: (773) 834-0505
E-mail: ncox@bsd.uchicago.edu

Marital Status:

Married, 2 children

Education

1978 B.Sc. Biology, The University of Notre Dame

1982 Ph.D. Human Genetics, Yale University

Professional Positions Held

1982-1985 Postdoctoral Fellow in Genetic Epidemiology Department of Psychiatry, Washington

University School of Medicine, St. Louis, MO

1985-1987 Research Associate, Department of Human Genetics, The University of Pennsylvania School of Medicine, Philadelphia, PA

1987-1990 Research Associate, Howard Hughes Medical Institute, The University of Chicago

1988-1990 Research Associate (Assistant Professor), Department of Medicine, The University of Chicago

1990-1996 Chief Research Technician, Department of Medicine, The University of Chicago

1996-1999 Research Associate (Assistant Professor), Department of Medicine, The University of Chicago, Associate Professor, Departments of Human Genetics and Medicine, The University of Chicago

2004-Present Professor, Departments of Human Genetics and Medicine, The University of Chicago

2005-Present Professor and Chief, Section of Genetic Medicine, Dept. of Medicine, The University of Chicago

Honors and Awards

Notre Dame Scholar, The University of Notre Dame, 1974-1978

Central Illinois Public Service Company Scholarship Award, 1974-1978

Notre Dame Scholarship, The University of Notre Dame, 1977-1978

National Research Service Award, Yale University, 1978-1981

Professional Activities

National Editorial Board - Diabetes 1993-1996

Member of Congressionally Mandated Diabetes Working Group 1998-1999

Member of Mammalian Genetics Study Section 1999-2003

Genetics Advisory Committee, NIDDK Phoenix, 1999-present

Scientific Advisory Board, Joslin Diabetes Center, 2000-2003

External Review Committee, Department of Human Genetics, The University of Utah, 2001

American Society of Human Genetics National Program Committee 2002-2004

American Diabetes Association National Program Committee 2004-present

Chair, Data Safety Monitoring Board, NHLBI Gene X Environment Studies, 2003-2006

Board of Scientific Counselors for NHGRI 2003-2008

Editor-in-Chief, Genetic Epidemiology

Editorial Board, American Journal of Human Genetics

University Service

The University of Chicago Admissions Committee Molecular Biosciences Cluster 1999-2003, Chair 2003

Committee on Research Resources 1999-2003

Aims Scientific Committee 2003

Steering Committee for Committee on Genetics 2001- present

Director of Graduate Studies and Curriculum Committee, Department of Human Genetics, 2002-2005

Committee on Academic Promotions 2004-present

Membership in Professional and Scientific Societies

American Society of Human Genetics

AAAS

International Society of Genetic Epidemiology

American Diabetes Association

Grant Support

06/15/06 -05/31/09 NIH/NHLBI $188,419, 5% effort, “Geome-wide Association Mapping of Metabolic, Lung, and Cardiovascular Phenotypes”, (P.I. Nancy J. Cox)

05/15/06-04/30/08, NIH/NIDDK, $133,137, 10% effort, “Copy-number Polymorphism Análisis of the Type 2 Diabetes Gene Calpain 10”, (P.I. Nancy J. Cox)

09/30/98-08/31/06, NIH/NIDDK, $225,000, 20% effort, “Robust Methods for Identifying Genes for Complex Traits”, (P.I. Nancy J. Cox)

09/01/99-08/31/06 , NIH/NIDDK , $628,433, 10% effort, “Consortium Linkage Studies of Type 2 Diabetes”, (P.I. Nancy J. Cox)

12/01/97-11/30/07, NIH/NIDDK, $1,287,129, 10% effort, “DRTC--Diabetes Research and Training Center”, (P.I. Steiner)

07/11/02-06/30/07, NIH/NIMH, 5% effort, “Multi-disciplinary Genetics Training Program”, (P.I. Gershon)

05/26/00 -Indefinite, Warner-Lambert Company, $100,000, “Analytic Approaches for Positional Cloning of Gene Influence”, (P.I. Nancy J. Cox)

Teaching

Human Genetics GEN 470, Course Director/6 lectures per year, 1998-2001

Human Variations 469, 6 lectures per year, 2001

Introduction to Statistical Genetics 471, 17 lectures per year, 2002-present

Past Postdoctoral Fellow Trainees

Susan Colilla, Ph.D., 1998-2002, currently in Epidemiology and Public Health, The University of Pennsylvania

Anya Tsalenko, Ph.D., 1997-2001, currently with Agilent Technologies

Anna Pluzhnikov, Ph.D., 1999-2001, currently Laboratory Manager, Department of Human Genetics, The University of Chicago

Mark Abney, Ph.D., 1997-2001, currently Research Associate (Assistant Professor), Department of Human Genetics, The University of Chicago

Marcos Antezana, Ph.D., 2003–2004, currently Research Associate, Department of Ecology and Evolution, The University of Chicago

Yu-Sheng Chen, Ph.D., 2003-2005

Maggie Ng, Ph.D., 2003-2006, currently Assistant Professor, Chinese University of Hong Kong

Current Postdoctoral Fellow Trainees

Geoffrey Hayes, Ph.D.

Past Graduate/Undergraduate Student Trainees

Nicoline Ambrose, PhD, 1996, currently Associate Professor, Department of Speech and Hearing Sciences, The University of Illinois at Champaign-Urbana

Benjamin Voight, Ph.D., 2006, currently post-doctoral fellow, the Broad Institute, Boston, MA

Current Graduate/Undergraduate Student Trainees

Jaqueline K. Wittke-Thompson

Peer Reviewed Articles

Cox, N.J . and Kidd, K.K. (1983) Can recovery from stuttering be considered a genetically milder subtype of stuttering? Behav Genet 13:129-139.

Dorus, E., Cox, N.J., Gibbon, R.D., Shaughnessy, R., Pandey, G.N. and Cloninger, C.R. (1983) Lithium ion transport and affective disorders within families of bipolar patients: Identification of a major gene locus. Arch Gen Psychiat 40:545-552.

Cox, N.J. , Seider, R.A. and Kidd, K.K. (1984) Some environmental factors and hypotheses for stuttering in families with several stutterers. J Speech Hear Res 27:543-548.

Cox, N.J. (1984) Genetic Analysis Workshop II: Results of segregation analyses using POINTER and linkage analyses using LIPED. Genet Epidem 1:167-170.

Cox, N.J. , Kramer, P.L. and Kidd, K.K. (1984) Segregation analyses of stuttering. Genet Epidem 1:245-253.

Goldin, L.R., Cox, N.J., Pauls, D.L., Gershon, E.L. and Kidd, K.K. (1984) The detection of major loci by segregation and linkage analysis: A simulation study. Genet Epidem 1:285-296.

Cox, N.J. and Suarez, B.K. (1985) Genetic Analysis Workshop III: Two-point linkage analysis on pedigrees, nuclear families, sibships. Genet Epidem 2:205-206.

Suarez, B.K. and Cox, N.J. (1985) Linkage analysis for psychiatric disorders. I. Basic concepts. Psychiat Dev 3:219-243.

Cox, N.J. and Suarez, B.K. (1985) Linkage analysis for psychiatric disorders. II. Methodological considerations. Psychiat Dev 4:369-382.

Ewens, W.J., Shute, N.C.E., Cox, N.J., Price, R.A. and Spielman, R.S. (1986) Ascertainment considerations in the analysis of affected sib shared haplotype data. Genet Epidem Suppl 1:319-322.

Cox, N.J. , Xiang, K., Bell, G.I. and Karam, J.H. (1988) Glucose transporter gene and non-insulin-dependent diabetes. Lancet II:793-794 (letter).

Vinik, A.I., Cox, N.J., Xiang, K-S., Fajans, S.S. and Bell, G.I. (1988) Linkage studies of maturity onset diabetes of the young -- R.W. pedigree. Diabetologia 31:778-780 (letter).

Cox, N.J. , Baker, L. and Spielman, R.S. (1988) Insulin gene sharing in sib pairs with insulin-dependent diabetes mellitus: No evidence for linkage. Am J Hum Genet 42:167-172.

Price, R.A., Cox, N.J., Spielman, R.S., Van Loon, J.A., Maidak, B.L. and Weinshilboum, R.M. (1988) Inheritance of human platelet thermolabile phenol sulfotransferase (TL PST) activity. Genet Epidem 5:1-16.

Cox, N.J. , Hodge, S.E., Marazita, M.L., Spence, M.A. and Kidd, K.K. (1988) Some effects of selection strategies on linkage analysis. Genet Epidem 5:289-297.

Cox, N.J. , Bell, G.I. and Xiang, K. (1988) Linkage disequilibrium in the insulin/insulin-like growth factor II region of human chromosome 11. Am J Hum Genet 43:495-501.

Cox, N.J. , Mela, A.P., Zmijewski, C.M. and Spielman, R.S. (1988) HLA-DR typing "at the DNA level": RFLP's and subtypes detected with a DR-beta cDNA probe. Am J Hum Genet 43:954-963.

Rajput-Williams, J., Knott, T.J., Wallis, S.C., Sweetnam, P., Yarnell, J., Cox, N.J., Bell, G.I., Miller, N.E. and Scott, J. (1988) Variation of apolipoprotein-B gene is associated with obesity, elevated blood cholesterol levels and coronary heart disease. Lancet ii:1442-1446.

Xiang, K.S., Bell, G.I., Karam, J.H., Cox, N.J., Sanz, N. and Huang, P. (1988) The association of genes responsible for carbohydrate and lipid metabolism in Chinese with non-insulin-dependent diabetes mellitus. J Chinese Med 68:552-556 [in Chinese].

Baur, M.P., Fimmers, R., Fritsche, R., et al. (1989) Genetic analysis of insulin-dependent diabetes mellitus (IDDM): The GAW5 multiplex family dataset. Genet Epidem 6:15-20.

Cox, N.J. , Gogolin, K.J., Horvath, V.J., Barker, D.F., Wright, E., Tran, T., Skolnick, M.H., Boehm, B.O., Fehsel, K., Bertrams, J., Hodge, T.W., Acton, R.T., McGill, J., Elbein, S.C., Permutt, M.A., de Preval, C., Avoustin, P., Cambon-Thomsen, A., Robinson, D.M., Holbeck, S.L., Nepom, G.T., Schneider, P.M., Rittner, C., Toyoda, H., Rotter, J.I. and Spielman, R. (1989) Restriction fragment polymorphisms of the HLA-DR, HLA-DQ and insulin gene regions in insulin-dependent diabetes mellitus families: The Genetic Analysis Workshop 5 data. Genet Epidem 6:21-26.

Cox, N.J. and Spielman, R.S. (1989) The insulin gene and susceptibility to IDDM. Genet Epidem 6:65-70.

Xiang, K., Cox, N.J., Sanz, N., Huang, P., Karam, J.H. and Bell, G.I. (1989) Insulin receptor and apolipoprotein genes contribute to the development of non-insulin-dependent diabetes mellitus in Chinese Americans. Diabetes 38:17-23.

Cox, N.J. , Epstein, P.A. and Spielman, R.S. (1989) Linkage studies on non-insulin-dependent diabetes mellitus (NIDDM) and the insulin and insulin receptor genes. Diabetes 38:653-658.

Cox, N.J. , Reich, T., Rice, J., Elston, R., Scober, J., Keats, B. (1989) Segregation and linkage analyses of bipolar and major depressive illnesses in multigenerational pedigrees. J Psychiat Res 23:109-123.

Cox, N.J. and Bell, G.I. (1989) Disease associations: Chance, artifact, or susceptibility genes? Diabetes 38:947-950.

Matsutani, A., Koranyi, L., Cox, N.J. and Permutt, M.A. (1990) Polymorphisms of GLUT2 and GLUT4 genes: use in evaluation of genetic susceptibility to NIDDM in Blacks. Diabetes 39:1534-1542.

Bell , G.I., Wu, S., Newman, M., Fajans, S.S., Seino, M., Seino, S. and Cox, N.J. (1991) Diabetes mellitus: Identification of susceptibility genes. In "Etiology of Human Disease at the DNA Level", edited by Lindsten J, and Pettersson U, Raven Press, New York, pp. 93-113.

Bell, G.I., Xiang, K., Newman, M.V., Wu, S., Wright, L.G., Fajans, S.S., Spielman, R.S. and Cox, N.J. (1991) Gene for non-insulin-dependent diabetes mellitus (maturity-onset diabetes of the young subtype) is linked to DNA polymorphism on human chromosome 20q. Proc Natl Acad Sci USA 88:1484-1488.

Mangklabruks, A., Billerbeck, A-E., Wajchenberg, B., Knobel, M., Cox, N.J., DeGroot, L.J. and Medeiros-Neto, G. (1991) Genetic linkage studies of thyroid peroxidase (TPO) gene in families with TPO deficiency. J Clin Endocrinol Metab 72:471-476.

Mangklabruks, A., Cox, N.J. and DeGroot, L. (1991) Genetic factors in autoimmune thyroid disease analyzed by restriction fragment length polymorphisms of candidate genes. J Clin Endocrinol Metab 73:236-244.

Kong, A., Frigge, M., Cox, N.J. and Wong, W.H. (1992) Linkage analysis with adjustment for covariates: A method combining peeling with Gibbs sampling. Genetic Analysis Workshop 7: Issues in Gene Mapping and Detection of Major Genes. MacCluer JW, Chakravarti A, Cox D, Bishop DT, Bale SJ, Skolnick MH (eds.) Cytogenet Cell Genet 59:208-211.

Cox, N.J. , Xiang, K.S., Fajans, S.S. and Bell, G.I. (1992) Mapping diabetes-susceptibility genes: Lessons learned from the search for a DNA marker for MODY. Diabetes 41:401-407.

Kong, A., Frigge, M., Irwin, M. and Cox, N.J. (1992) Importance sampling. I. Computing multi-model p values in linkage analysis. Am J Hum Genet 51:1413-1429.

Cox, N.J. (1993) Stuttering: A complex behavioral disorder for our times? Am J Med Genet (Neuropsychiatric Genetics) 48:177-178.

Stoffel, M., Xiang, K.S., Espinosa, III R., Cox, N.J., LeBeau, M.M. and Bell, G.I. (1993) cDNA sequence and localization of polymorphic human cytosolic phosphoenolpyruvate carboxykinase gene (PCK1) to choromosome 20, band q13.31: PCK1 is not tightly linked to maturity-onset diabetes of the young. Hum Mol Genet 2:1-4.

Lewis, B.A., Cox, N.J. and Byard, P.J. (1993) Segregation analysis of speech and language disorders. Behav Genet 23:291-297.

Ambrose, N., Yairi, E. and Cox, N.J. (1993) Genetic aspects of early childhood stuttering. J Speech Hear Res 36:701-706.

Kong, A., Irwin, M., Cox, N.J. and Frigge, M. (1993) Sequential imputation in multilocus linkage analysis. Genet Epidemiol 10:483-488.

Cox, N.J. (1994) Maternal component in NIDDM transmission: How large an effect? Diabetes 43:166-168.

Kass, S., MacRae, C., Graber, H.L., Sparks, E.A., McNamara, D., Boudoulas, H., Basson, C.T., Baker, P.B. III, Cody, R.J., Fishman, M.C., Cox, N.J., Kong, A., Wooley, C.F., Seidman, J.G. and Seidman, C.E. (1994) A gene defect that causes conduction system disease and dilated cardiomyopathy maps to chromosome 1p1-1q1. Nature Genet 7:546-551.

Irwin, M., Cox, N.J. and Kong, C.A. (1994) Sequential imputation for multilocus linkage analysis. Proc Natl Acad Sci USA 91:11684-11688.

Weiss, R.E., Sunthornthepvarakul, T., Angkeow, P., Marcus-Bagley, D., Cox, N.J., Alper, C.A. and Refetoff, S. (1994) Linkage of familial dysalbuminemic hyperthyroxinemia to the albumin gene in a large Amish kindred. J Clin Endocrinol Metab 80:116-121.

Cook, E.H., Stein. M.A., Krasowski, M.D., Cox, N.J., Olkon, D.M., Keiffer, J.E. and Leventhal, B.L. (1995) Association of attention-deficit disorder and the dopamine transporter gene. Am J Hum Genet 56:993-998.

Tsaar, M.L., Menzel, S., Lai, F.P., Espinosa, III R., Concannon, P., Spielman, R.S., Hanis, C.L., Cox, N.J., Le Beau, M.M., German, M.S., Jan, L.Y., Bell, G.I. and Stoffel, M. (1995) Isolation of a cDNA clone encoding a K ATP-channel-like protein expressed in insulin-secreting cells, localization of the human gene to chromosome band 21q22.1, and linkage studies with NIDDM. Diabetes 44:592-596.

Glaser, B., Chiu, K.C., Liu, L., Anker, R., Nestorowicz, A., Cox, N.J., Landau, H., Kaiser, N., Thornton, P.S., Stanley, C.A., Cerasi, E., Baker, L., Donis-Keller, H. and Permutt, M.A. (1995) Recombinant mapping of the familial hyperinsulinism gene to an 0.8 cM region on chromosome 11p15.1 and demonstration of a founder effect in Ashkenazi Jews. Hum Mol Genet 4:879-886.

Stirling, B., Cox, N.J., Bell, G.I., Hanis, C.L., Spielman, R.S. and Concannon, P. (1995) Identification of microsatellite markers near the human ob gene and linkage studies in NIDDM affected sib pairs. Diabetes 44:999-1001.

Menzel, S., Yamagata, K., Trabb, J.B., Nerup, J., Permutt, M.A., Fajans, S.S., Menzel, R., Iwasaki, N., Omori, Y., Cox, N.J. and Bell, G.I. (1995) Localization of MODY3 to a 5 cM region of human chromosome 12. Diabetes 44:1408-1413.

Stirling, B., Cox, N.J., Bell, G.I., Hanis, C.L., Spielman, R.S. and Concannon, P. (1995) Linkage studies in NIDDM with markers near the sulfonylurea receptor gene. Diabetologia 38:1479-1481.

Shoulders, C.C., Grantham, T.T., North, J.D., Gaspardone, A., Tomai, F., DeFazio, A., Versaci, F., Gioffre, P.A. and Cox, N.J. (1996) Hypertriglyceridemia and the apolipoprotein III gene locus: lack of association with the variant insulin response element in Italian school children. Hum Genet 98:557-566.

Iwasaki, N., Kawamura, M., Yamagata, K., Cox, N.J., Karibe, S., Ohgawara, H., Inagaki, N., Seino, S., Bell, G.I. and Omori, Y. (1996) Identification of microsatellite markers near the human genes encoding the β-cell ATP-sensitive potassium channel and linkage studies with NIDDM in Japanese. Diabetes 45:267-269.

Gambino, V., Menzel, S., Trabb, J.B., Xiang, K.S., Lindner, T., Louït, A., Chen, E., Mereu, L.E., Furuta, H., Iwasaki, N., Kawamura, M., Omori, Y., Rietzsch, H., Schulze, J., Schröder, H.E., Concannon, P., Hanis, C.L., Spielman, R.S., Yamagata, K., Cox, N.J. and Bell, G.I. (1996) An approach for identifying simple sequences repeat DNA polymorphisms near cloned cDNAs and genes: linkage studies of the islet amyloid polypeptide/amylin and liver glycogen synthase genes and NIDDM. Diabetes 45:291-294.

Hanis, C.L., Boerwinkle, E., Chakraborty, R., Ellsworth, D.L., Concannon, P., Stirling, B., Morrison, V.A., Wapelhorst, B., Spielman, R.S., Goglin-Ewens, K.J., Shephard, J.M., Williams, S.R., Risch, N., Hinds, D., Iwasaki, N., Ogata, M., Omori, Y., Petzold, C., Rietzsch, H., Schröder, H.E., Schulze, J., Cox, N.J., Menzel, S., Boriraj, V.V., Chen, X., Lim, L.R., Lindner, T., Mereu, L.E., Wang, Y.Q., Xiang, K.S., Yamagata, K., Yang, Y. and Bell, G.I. (1996) A genome-wide search for human non-insulin-dependent (Type 2) diabetes genes reveals a major susceptibility locus on chromosome 2. Nature Genet 13:161-167.

Stoffel, M., Le Beau, M.M., Espinosa, III R., Bohlander, S.F., Le Paslier, D., Cohen, D., Xiang, K-S., Cox, N.J., Fajans, S.S. and Bell, G.I. (1996) A yeast artificial chromosome-based map of the region of chromosome 20 containing the diabetes-susceptibility gene, MODY 1, and a myeloid leukemia related gene Proc Natl Acad Sci USA 93:3937-3941.

Yamagata, K., Takeda, J., Menzel, S., Chen, X., Eng, S., Lim, L.R., Concannon, P., Hanis, C.L., Spielman, R.S., Cox, N.J. and Bell, G.I. (1996) Searching for NIDDM susceptibility genes: studies of genes with triplet repeats expressed in skeletal muscle. Diabetologia 39:725-730.

Iwasaki, N., Kawamura, M., Ohgawara, H., Karibe, S., Cox, N.J., Bell, G.I. and Omori, Y. (1996) Sib-pair analysis of Japanese NIDDM patients. J Japan Diab Soc 39:409-416 [in Japanese].

Yamagata, K., Oda, N., Kaisaki, P.J., Menzel, S., Furuta, H., Vaxillaire, M., Southam, L., Cox, R.D., Lathrop, M., Boriraj, V.V., Chen, X., Cox, N.J., Oda, Y., Yano, H., Le Beau, M.M., Yamada, S., Nishigori, H., Takeda, J., Fajans, S.S., Hattersley, A.T., Iwasaki, N., Hansen, T., Pedersen, O., Polonsky, K.S., Turner, R.C., Velho, G., Chèvre, J.C., Froguel, P. and Bell, G.I. (1996) Mutations in the hepatocyte nuclear factor-1 a gene in maturity-onset diabetes of the young (MODY3). Nature 384:455-458.

Yamagata , K., Furuta, H., Oda, N., Kaisaki, P.J., Menzel, S., Cox, N.J., Fajans, S.S., Signorini, S., Stoffel, M. and Bell, G.I. (1996) Mutations in the hepatocyte nuclear factor-4 a gene in maturity-onset diabetes of the young (MODY1). Nature 384:458-460.

Kong, A., Frigge, M., Bell, G.I., Lander, E., Daly, M. and Cox, N.J. (1997) Diabetes, dependence, asymptotics, significance, and selection. (Letter) Nature Genet 17:148.

Cook, E.H., Courchesne, R., Lord, C., Cox, N.J., Yan, S., Lincoln, A., Haas, R., Courchesne, E. and Leventhal, B.L. (1997) Evidence of linkage between the serotonin transporter and autistic disorder. Mol Psych 2:247-250.

Ober, C., Cox, N.J., Lester, L.A., Peterson, R., Gidley, H., Pluzhnikov, A., Anderson, J., Solway, J., Leff, A., Wolf, R., Wylam, M., Kurtz, B., Richardson, A. and Parry, R. (1997) A genome-wide search for asthma susceptibility loci in ethnically diverse populations: the collaborative study on the genetics of asthma (CSGA). Nature Genet 15:389-392.

Bell , G.I., Cox, N.J., Lindner, T., Concannon, P., Spielman, R.S., Boerwinkle, E. and Hanis, C.L. (1997) Genetics of NIDDM in the Mexican Americans of Starr County, Texas: an update. Diabetes Reviews 5:277-283.

Boehnke, M. and Cox, N.J. (1997) Accurate inference of relationships in sib-pair linkage studies. Am J Hum Genet 61:423-429.

Ober, C., Weitkamp, L.R., Cox, N.J., Dytch, H., Kostyu, D., Elias, S. (1997) HLA and mate choice in humans. Am J Hum Genet 61:497-504.

Ambrose, N.G., Cox, N.J., Yairi, E. (1997) The genetic basis of persistence and recovery in stuttering. J Speech, Language, Hear Res 40:567-580.

Kong, A. and Cox, N.J. (1997) Allele sharing models: LOD scores and accurate linkage tests. Am J Hum Genet 61:1179-1188.

Lindner, T., Gragnoli, C., Schulze, J., Rietzsch, H., Petzold, C., Schröder, H.E., Cox, N.J. and Bell, G.I. (1997) The 31-cM region of chromosome 11 including the obesity gene Tubby and ATP-sensitive potassium channel genes, SUR1 and Kir6.2 does not contain a major susceptibility locus for NIDDM in 127 non-Hispanic white affected sibships. Diabetes 46:1227-1229.

Kong, A., Frigge, M., Bell, G.I., Lander, E., Daly, M. and Cox, N.J. (1997) Diabetes, dependence, asymptotics, significance and selection. Nature Genet 17:148.

Ober, C. and Cox, N.J. (1998) Mapping genes for complex traits in founder populations. Clin Exper Allergy 28:101-105.

Cook, E.H., Courchesne, R.Y., Cox, N.J., Lord, C., Pizzo, S., Gonen, D., Guter, S.J., Lincoln, A., Nix, K., Haas, R., Leventhal, B.L., Courchesne, E. (1998) Linkage disequilibrium mapping with 15q11-13 markers in autistic disorder. Am J Hum Genet 62:1077-1083.

Ober, C., Cox, N.J., Abney, M., Di Rienzo, A., Lander, E.S., Changyaleket, B., Gidley, H., Kurtz, B., Lee, J., Nance, M., Petterson, A., Prescott, J., Richardson, A., Schlenker, E., Summerhill, E., Willadsen, S., Parry, R. and the Collaborative Study on the Genetics of Asthma. (1998) Genome-wide search for asthma susceptibility loci in a founder population. Hum Molec Genet 7:1393-1398.

Concannon, P., Gogolin-Ewens, K.J., Hinds, D.A., Wapelhorst, B., Morrison, V.A., Stirling, B., Mitra, M., Farmer, J., Williams, S.R., Cox, N.J., Bell, G.I., Risch, N., and Spielman, R.S. (1998) A second generations screen of the human genome for susceptibility to insulin-dependent diabetes mellitus. Nature Genet 19:292-296.

Cox, N.J. , Frigge, M., Nicolae, D.L., Concannon, P., Hanis, C.L., Bell, G.I. and Kong, A. (1999) Loci on chromosomes 2 (NIDDM1) and 15 interact to increase susceptibility to type 2 diabetes. Nature Genet 21:213-215.

Pannain, S., Weiss, R.E., Jackson, C.E., Dian, D., Beck, J.C., Sheffield, V., Cox, N.J. and Refetoff, S. (1999) Two different mutations in the thyroid peroxidase gene of a large inbred Amish kindred: Power and limits of homozygosity mapping. J Clin Endocrinol Metab 84:1061-1071.

Ober, C., Tsalenko, A., Willadsen, S.A., Newman, D.L., Daniel, R., Wu, X., Andal, J., Cox, N.J. (1999) Genome-wide screen for atopy susceptibility alleles in the Hutterites. Clin Exp Allergy Suppl 4:11-15.

Hinokio, Y., Horikawa, Y., Furuta, H., Cox, N.J., Iwasaki, N., Honda, M., Ogata, M., Iwamoto, Y., and Bell, G.I. (2000) b -Cell Transcription factors and diabetes: no evidence for diabetes-associated mutations in the hepatocyte nuclear factor-3 b gene (HNF3B) in Japanese patients with maturity-onset diabetes of the young. Diabetes 49:302-305.

Ober, C., Leavitt, S.A., Tsalenko, A., Howard, T.D., Hoki, D.M., Daniel, R., Newman, D.L., Wu, X., Parry, R., Lester, L.A., Solway, J., Blumenthal, M., King, R.A., Xu, J., Meyers, D.A., Bleecker, E.R. and Cox, N.J. (2000) Variation in the interleukin 4-receptor a gene confers susceptibility to asthma and atopy in ethnically diverse populations. Am J Hum Genet 66:517-526.

Baier, L.J., Permana, P.A., Yang, X., Pratley, R.E., Hanson, R.L., Shen, G-Q., Mott, D., Knowler, W.C., Cox, N.J., Horikawa, Y., Oda, N., Bell, G.I. and Bogardus, C. (2000) A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance. J Clin Invest 106:R69-R73.

Horikawa, Y., Oda, N., Cox, N.J., Li, X., Orho-Melander, M., Hara, M., Hinokio, Y., Lindner, T.H., Mashima, H., Schwarz, P.E.H., del Bosque-Plata, L., Horikawa, Y., Oda, Y., Yoshiuchi, I., Colilla, S., Polonsky, K.S., Shan, W., Concannon, P., Iwasaki, N., Schulze, J., Baier, L.J., Boguardus, C., Groop, L., Boerwinkle, E., Hanis, C.L. and Bell, G.I. (2000) Genetic variation in the calpain 10 gene (CAPN10) is associated with type 2 diabetes mellitus. Nature Genet 126:163-175.

Ober, C., Tsalenko, A., Parry, R. and Cox, N.J. (2000) A second-generations genomewide screen for asthma-susceptibility alleles in a founder population. Am J Hum Genet 67:1154-1162.

Hara, M., Wang, X., Paz, V.P., Cox, N.J., Iwasaki, N., Ogata, M., Iwamoto, Y. and Bell, G.I. (2000) No diabetes-associated mutations in the coding region of the hepatocyte nuclear factor-4gamma gene (HNF4G) in Japanese patients with MODY. Diabetologia 43:1064-9.

Horikawa, Y., Horikawa, Y., Cox, N.J., Iwasaki, N., Ogata, M., Iwamoto, Y., Schwitzgebel, V., German, M.S. and Bell, G.I. (2000) Beta-cell transcription factors and diabetes: no evidence for diabetes-associated mutations in the gene encoding the basic helix-loop-helix transcription factor neurogenic differentiation 4 (NEUROD4) in Japanese patients with MODY. Diabetes. 49:1955-1957.

Cox, N.J. (2001) Introduction: interactions in asthma. Genet Epidemiol 21:S264-265.

Colilla, S., Tsalenko, A., Pluznikov, A. and Cox, N.J. (2001) Genome-wide approaches for identifying interacting susceptibility regions for asthma. Genet Epidemiol 21:S266-271.

Evans, J.C., Frayling, T.M., Cassell, P.G., Saker, P.J., Hitman, G.A., Walker, M., Levy, J.C., O’Rahilly, S., Rao, P.V.S., Bennett, A.J., Jones, E.C., Menzel, S., Prestwich, P., Simecek, N., Wishart, M., Dhillon, R., Fletcher, C., Millward, A., Demaine, A., Wilkin, T., Horikawa, Y., Cox, N.J., Bell, G.I., Ellard, S., McCarthy MI, Hattersley AT (2001) Studies of association between the gene for calpain-10 and type 2 diabetes mellitus in the United Kingdom. Am J Hum Genet 69:544-552.

Xu, J., Meyers, D.A., Ober, C., Blumenthal, M.N., Mellen, B., Barnes, K.C., King, R.A., Lester, L.A., Howard, T.D., Solway, J., Langefeld, C.D., Beaty, T.H., Rich, S.S., Bleecker, E.R. and Cox, N.J. (2001) Genomewide screen and identification of gene-gene interactions for asthma-susceptibility loci in three U.S. populations: Collaborative study on the genetics of asthma. Am J Hum Genet 68:1437-1446.

Colilla, S., Cox, N.J. and Ehrmann, D.A. (2001) Heritability of insulin secretion and insulin action in women with polycystic ovary syndrome and their first degree relatives. J Clin Endocrinol Metab 86:2027-2031.

del Bosque-Plata, L., Lin, J., Horikawa, Y., Schwarz, P.E., Cox, N.J., Iwasaki, N., Ogata, M., Iwamoto, Y., German, M.S. and Bell, G.I. (2001) Mutations in the coding region of the neurogenin 3 gene (NEUOROG3) are not a common cause of maturity-onset diabetes of the young in Japanese subjects. Diabetes 50:694-696.

Mathias, R.A., Freidhoff, L.R., Blumenthal, M.N., Meyers, D.A., Lester, L., King, R., Xu, J.F., Solway, J., Barnes, K.C., Pierce, J., Stine, O.C., Togias, A., Oetting, W., Marshik, P.L., Hetmanski, J.B., Huang, S.K., Ehrlich, E., Dunston, G.M., Malveaux, F., Banks-Schlegel, S., Cox, N.J., Bleecker, E., Ober, C., Beaty, T.H. and Rich, S.S. (2001) Genome-wide linkage analyses of total serum IgE using variance components analysis in asthmatic families. Genet Epidemiol. 20:340-355.

Cox, N.J. , Wapelhorst, B., Morrison, V.A., Johnson, L., Pinchuk, L., Spielman, R.S., Todd, J.A., Concannon, P. (2001) Seven regions of the genome show evidence of linkage to type 1 diabetes in a consensus analysis of 767 multiplex families. Am J Hum Genet 69:820-830

Sreenan, S.K., Zhou, Y-P., Otani, K., Hansen, P.A., Currie, K.P.M., Pan, C-Y., Lee, J-P., Ostrega, D.M., Pugh, W., Horikawa, Y., Cox, N.J., Hanis, C.L., Burant, C.F., Fox, A.P., Bell, G.I. and Polonsky, K.S. (2001) Calpains play a role in insulin secretion and action. Diabetes 50:2013-2020.

Cox, N.J. (2001) Challenges in identifying genetic variation affecting susceptibility to type 2 diabetes: Examples from studies of the calpain-10 gene. Hum Molec Genet 10:2301-2305.

Newman, D.L., Abney, M., McPeek, M.S., Ober, C. and Cox, N.J. (2001) The importance of genealogy in determining genetic associations with complex traits. Am J Hum Genet 69:1146-1148.

Cox, N.J. (2001) Computational issues in mapping variation affecting susceptibility to complex disorders: the chicken and the egg. Theor Popul Biol 60:221-25.

Nicolae, D.L. and Cox, N.J. (2002) MERLIN...and the geneticist's stone? Nat Genet 30:3-4. Invited commentary

Lynn, S., Evans, J.C., White, C., Frayling, T.M., Hattersley, A.T., Turnbull, D.M., Horikawa, Y., Cox, N.J., Bell, G.I. and Walker, M. (2002) Variation in the calpain-10 gene affects blood glucose levels in the British population. Diabetes 51:247-250.

Sun, L., Cox, N.J. and McPeek, M.S. (2002) A statistical method for identification of polymorphisms that explain a linkage result. Am J Hum Genet. 70:399-411.

Elbein, S.C., Chu, W., Ren, Q., Hemphill, C., Schay, J., Cox, N.J., Hanis, C.L. and Hasstedt, S.J. (2002) Role of calpain-10 gene variants in familial type 2 diabetes in Caucasians. J Clin Endocrinol Metab 87:650-654.

Hara, M., Alcoser, S.Y., Qaadir, A., Beiswenger, K.K., Cox, N.J. and Ehrmann, D.A. (2002) Insulin resistance is attenuated in women with polycystic ovary syndrome with the Pro(12)Ala polymorphism in the PPARgamma gene. J Clin Endocrinol Metab 87:772-775.

Fullerton, S.M., Bartoszewicz, A., Ybazeta, G., Horikawa, Y., Bell, G.I., Kidd, K.K., Cox, N.J., Hudson, R.R. and Di Rienzo, A. (2002) Geographic and haplotype structure of candidate type 2 diabetes susceptibility variants at the calpain-10 locus. Am J Hum Genet 70:1096-1106.

Ehrmann, D. A., Schwartz, P. E. H., Hara, M., Tang, X., Horikawa, Y., Imperial, J., Bell, G. I., Cox, N. J. (2002) Relationship of calpain-10 genotype to phenotypic features of polycystic ovary syndrome. J. Clin. Endocrinol. Metab. 87:1669-1673.

Haddad, L., Evans, J.C., Gharani, N., Robertson, C., Rush, K., Wiltshire, S., Frayling, T.M., Wilkin, T.J., Demaine, A., Millward, A., Hattersley, A.T., Conway, G., Cox, N.J., Bell, G.I., Franks, S. and McCarthy, M.I. (2002) Variation within the type 2 diabetes susceptibility gene calpain-10 and polycystic ovary syndrome. J Clin Endocrinol Metab 87:2606-2610.

Cox, N.J. (2002) Calpain 10 and genetics of type 2 diabetes. Curr Diab Rep. 2:186-90.

Pritchard, J.K. and Cox, N.J. (2002) The allelic architecture of human disease genes: common disease—common variant—or not? Human Molecular Genetics 11:2417-2423.

Rasmussen, S.K., Urhammer, S.A., Berglund, L., Jensen, J.N., Hansen, L., Echwald, S.M., Borch-Johnsen, K., Horikawa, Y., Mashima, H., Lithell, H., Cox, N.J., Hansen, T., Bell, G.I., Pederson, O. (2002) Variants within the calpain-10 gene on chromosome 2q37 (NIDDM1) and relationships to type 2 diabetes, insulin resistance, and impaired acute insulin secretion among Scandinavian Caucasians. Diabetes 51(12):3561-3567.

Ehrmann, D.A., Tang, X., Yoshiuchi, I., Cox, N.J., Bell, G.I. (2002) Relationship of insulin receptor substrate-1 and -2 genotypes to phenotypic features of polycystic ovary syndrome. J Clin Endocrinol Metab 87(9):4297-4300.

Hanna, G.L., Vennstra-VanderWeele, J., Cox, N.J., Boehnke, M., Himle, J.A., Curtis, G.C., Leventhal, B.L., Cook, E.H. Jr. (2002) Genome-wide linkage analysis of families with obsessive-compulsive disorder ascertained through pediatric probans. Am J Med Genet 114(5):541-52.

Colilla, S., Nicolae, D., Pluzhnikov, A., Blumethal, M.N., Beaty, T.H., Bleecker, E.R., Lange, E.M., Rich, S.S., Meyers, D.A., Ober, C., Cox, N.J., and the CSGA (2003) Evidence for gene-environment interactions in a linkage study of asthma and smoking exposure. J Allergy Clin Immunol 111(4):840-846.

Zhou, Y.P., Sreenan, S., Pan, C.Y., Currie, K.P., Bindokas, V.P., Horikawa, Y., Lee, J.P., Ostrega, D., Ahmed, N., Balswin, A.C., Cox, N.J., Fox, A.P., Miller, R.J., Bell, G.I., Polonsky, K.S. (2003) A 48-hour exposure of pancreatic islets to calpain inhibitors impairs mitochondrial fuel metabolism and the exocytosis of insulin. Metabolism 52(5):528-534.

Canizales-Quinteros, S., Aguilar-Salinas, C.A., Reyes-Rodriguez, E., Riba, L., Rodriguez-Torres, M., Ramirez-Jimenez, S., Huertas-Vazquez, A., Fragoso-Onitveros, V., Zentell-Dehesa, A. Ventura-Gallegos, J. L., Vega-Hernandez, G., Lopez-Estrada, A., Auron-Gomex-Perez, F., Rull, J., Cox, N.J., Bell, G.I., Tusie-Luna, M.T. (2003) Locus on chromosome 6p linked to elevated HDL cholesterol serum levels and to protection against premature atherosclerosis in a kindred with familial hypercholesterolemia. Circ Res 92(5):569-576.

Tsalenko A., Ben-Dor A., Cox, N.J., Yakhini, Z. (2003) Methods for analysis and visualization of SNP genotype data for complex diseases. Pac Symp Biocomput. 548-61.

Iwasaki, N., Cox, N.J., Wang, Y.Q., Schwartz, P.E., Bell, G.I., Honda, M., Imura, M., Ogata, M., Saito, M., Kamatani, N., Iwamoto, Y. (2003) Mapping genes influencing type 2 diabetes risk and BMI in Japanese subjects. Diabetes 52(1):209-13.

Naoumova, R.P., Bonney, S.A., Eichenbaum-Voline, S., Patel, H.N., Jones, B., Jones, E.L., Amey, J., Solilla, S., Neuwirth, C.K., Allotey, R., Seed, M., Betteridge, D.J., Galton, D.J., Cox, N.J., Bell, G.I., Scott, J., Shoulders, C.C. (2003) Confirmed Locus on chromosome 11p and candidate loci on 6q and 8p for the triglyceride and cholesterol traits of combined hyperlipidemia. Arterioscler Thromb Vasc Biol. 23 (11):2070-7.

Ng, M.C., So, W.Y., Cox, N.J., Lam, V.K., Cockram, C.S., Critchley, J.A., Bell, G.I., Chan, J.C. (2004) Genome-wide Scan for Type 2 Diabetes Loci in Hong Kong Chinese and Confirmation of a Susceptibility Locus on Chromosome 1q21-q25. Diabetes. 53 (6):1609-13.

Cox, N.J. , Hayes, M.G., Roe, C.A., Tsuchiya, T., Bell, G.I. (2004) Linkage of calpain 10 to type 2 diabetes: the biological rationale. Diabetes. 53 Suppl 1:S19-25. Review.

del Bosque-Plata, L., Aguilar-Salinas, C.A., Tusie-Luna, M.T., Ramirez-Jimenez, S., Rodriguez-Torres, M., Auron-Gomez, M., Ramirez, E., Velasco-Perez, M.L., Ramirez-Silva, A., Gomez-Perez, F., Hanis, C.L., Tsuchiya, T., Yoshiuchi, I., Cox, N.J., Bell, G.I. (2004) Association of the calpain-10 gene with type 2 diabetes mellitus in a Mexican population. Mol Genet Metab 81 (2):122-6.

Chen, Y.S., Akula, N., Detera-Wadleigh, S.D., Schulze, T.G., Thomas, J., Potash, J.B., DePaulo, J.R., McInnis, M.G., Cox, N.J., McMahon, F.J. (2004) Findings in an independent sample support an association between bipolar affective disorder and the G72/G30 locus on chromosome 13q33. Mol Psychiatry. 9 (1):87-92.

Blumenthal, M.N., Langefeld, C.D., Beaty, T.H., Bleecker, E.R., Ober, C., Lester, L., Lange, E., Barnes, K.C., Wolf, R., King, R.A., Solway, J., Oetting, W., Meyers, D.A., Rich, S.S. (2004) A genome-wide search for allergic response (atopy) genes in three ethnic groups: Collaborative Study on the Genetics of Asthma. Hum Genet. 114(2):157-64.

Blumenthal, M.N., Ober, C., Beaty, T.H., Bleecker, E.R., Langefeld, C.D., King, R.A., Lester, L., Cox, N.J., Barnes, K., Togias, A., Mathias, R., Meyers, D.A., Oetting, W., Rich, S.S. for the CSGA (2004) Genome scan for loci linked to mite sensitivity: the Collaborative Study on the Genetics of Asthma (CSGA). Genes and Immunity (2004), 1-6.

Ng, M.C., So, W.Y., Lam, V.K., Cockram, C.S., Bell, G.I., Cox, N.J., Chan, J.C. (2004) Genome-wide scan for metabolic syndrome and related quantitative traits in Hong Kong Chinese and confirmation of a susceptibility locus on chromosome 1q21-q25. Diabetes 53(10):2676-83.

Schulze, T.G., Buervenich, S., Badner, J.A., Steele, C.J., Detera-Wadleigh, S.D., Dick, D., Foroud, T., Cox, N.J., MacKinnon, D.F., Potash, J.B., Berrettini, W.H., Byerley, W., Coryell, W., DePaulo, J.R. Jr, Gershon, E.S., Kelsoe, J.R., McInnis, M.G., Murphy, D.L., Reich, T., Scheftner, W., Nurnberger, J.I. Jr, McMahon, F.J. (2004) Loci on chromosomes 6q and 6p interact to increase susceptibility to bipolar affective disorder in the national institute of mental health genetics initiative pedigrees. Biol Psychiatry 56(1):18-23.

Cox N.J. (2004) Human genetics: an expression of interest. Nature 430(7001):733-4. Invited commentary

Nicolae, D., Cox, N.J., Lester, L.A., Schneider, D., Tan, Z., Billstrand, C., Kuldanek, S., Donfack, J., Kogut, P., Patel, N.M., Goodenbour, J., Howard, T., Wolf, R., Koppelman, G.H., White, S.R., Parry, R., Postma, D.S., Meyers, D., Bleecker, E.R., Hunt, J.S., Solway, J., Ober, C. (2005) Fine Mapping and Positional Candidate Studies Identify HLA-G as an Asthma Susceptibility Gene on Chromosome 6p21. Am J Hum Genet. 76(2):349-57.

Iwasaki, N., Horikawa, Y., Tsuchiya, T., Kitamura, Y., Nakamura, T., Tanizawa, Y., Oka, Y., Hara, K., Kadowaki, T., Awata, T., Honda, M., Yamashita, K., Oda, N., Yu, L., Yamada, N., Ogata, M., Kamatani, N., Iwamoto, Y., Del Bosque-Plata, L., Hayes, M.G., Cox, N.J., Bell, G.I. (2005) Genetic variants in the calpain-10 gene and the development of type 2 diabetes in the Japanese population. J Hum Genet 50(2):92-8.

125. Riaz, N., Steinberg, S., Ahmad, J., Pluzhnikov, A., Riazuddin, S., Cox, N.J., Drayna, D. (2005) Genomewide significant linkage to stuttering on chromosome 12. Am J Hum Genet 76(4):647-51.

Clark, V.J., Cox, N.J., Hammond, M., Hanis, C.L., Di Rienzo, A. (2005) Haplotype structure and phylogenetic shadowing of a hypervariable region in the CAPN10 gene. Hum Genet 117:258-66.

Wittke J.K., Pluzhnikov, A., Cox, N.J. (2005) Rational inferences about departures from Hardy-Weinberg equilibrium. Am J Hum Genet 76:967-86.

Ng, M.C.Y., Miyake, K., So, W.Y., Poon, E.W.M, Lam, V.K.L., Li, J.K.Y., Cox, N.J., Bell, G.I., Chan, J.C.N. (2005) The linkage and association of the gene encoding upstream stimulatory factor 1 with type 2 diabetes and metabolic syndrome in the Chinese population. Diabetologia 48:2018-24.

Hayes, M.G., del Bosque-Plata, L., Tsuchiya, T., Hanis, C.L., Bell, G.I., Cox, N.J. (2005) Patterns of linkage disequilibrium in the type 2 diabetes gene calpain-10. Diabetes 54:3573-6.

Suresh, R., Ambrose, N., Roe, C., Pluzhnikov, A., Wittke-Thompson, J.K., Ng, M.C., Wu, X., Cook, E.H., Lundstrom, C., Garsten, M., Ezrati, R., Yairi, E., Cox, N.J. (2006) New complexities in the genetics of stuttering: significant sex-specific linkage signals. Am J Hum Gene 78:554-63.

Suarez, B.K., Duan, J., Sanders, A.R., Hinrichs, A.L., Jin, C.H., Hou, C., Buccola, N.G., Hale, N., Weilbaecher, A.N., Nertney, D.A., Olincy, A., Green, S., Schaffer, A.W., Smith, C.J., Hannah, D.E., Rice, J.P., Cox, N.J., Martinez, M., Mowry, B.J., Amin, F., Silverman, J.M., Black, D.W., Byerley, W.F., Crowe, R.R., Freedman, R., Cloninger, C.R., Levinson, D.F., Gejman, P.V. (2006) Genomewide linkage scan of 409 European-Ancestry and African American families with schizophrenia: Suggestive evidence of linkage at 8p23.3-p21.2 and 11p13.1-q14.1 in the combined sample. Am J Hum Genet 78:315-33.

Dickel, D.E., Veenstra-Vanderweele, J., Cox, N.J., Wu, X., Fischer, D.J., Van Etten-Lee, M., Himle, J.A., Leventhal, B.L., Cook, E.H. Jr, Hanna, G.L. (2006) Association testing of the positional and functional candidate gene SLC1A1/EAAC1 in early-onset obsessive-compulsive disorder. Arch Gen Psychiat 63:776-85.

Nicolae, D.L., Wu, X., Miyake, K., Cox, N.J. (2006) GEL: A novel genotype calling algorithm using empirical likelihood. Bioinformatics (Epub ahead of print).

Pihlajamaki, J., Salmenniemi, U., Vanttinen, M., Ruotsalainen, E., Kuusisto, J., Vauhkonen, I., Kainulainen, S., Ng, M.C., Cox, N.J., Bell, G.I., Laakso, M. (2006) Common polymorphisms of calpain-10 are associated with abdominal obesity in subjects at high risk of type 2 diabetes. Diabetologia 49:1560-6.

Nicolae, D.L., Wen, X., Voight, B.F., Cox, N.J. (2006) Coverage and characteristics of the Affymetrix GeneChip Human Mapping 100K SNP set. PLoS Genet 2:e67.

Non-peer reviewed reports

Xiang, K., Cox, N.J., Hallewell, R.A., and Bell, G.I. (1987) Multiple Taq I RFLPs at the human manganese superoxide dismutase locus on chromosome 6. Nucl Acids Res 15:7654.

Xiang, K., Cox, N.J., Karam, J.H., and Bell, G.I. (1987) Bgl II RFLP at the human erythrocyte/HepG2-type glucose transporter (GLUT) locus on chromosome 1. Nucl Acids Res 15:9101.

Xiang, K., Cox, N.J., and Bell, G.I. (1988) Apa I and Sst I RFLPs at the insulin-like growth factor II (IGF2) locus on chromosome 11. Nucl Acids Res 16:3599.

Cox, N.J., Spielman, R.S., Kahn, C.R., Mueller-Weiland, D., Kriauciuinas, K.M., and Taub, R. (1988) Four RFLPs of the insulin receptor gene: Pst I, Kpn I, Rsa I (2 RFLPs). Nucl Acids Res 16:8204.

Cox, N.J. , Spielman, R.S., Kahn, C.R., Muller-Weiland, D., Kriauciuinas, K.M., and Taub, R. (1989) Four RFLPs of the insulin receptor gene: Pst I, Kpn I, Rsa I (2 RFLPs). Nucl Acids Res 17:820.

Book Chapters

Bell, G.I., Cockburn, B.N., Cox, N.J., Daniel, J.C., del Bosque Plata, L., Fajans, S.S., Gragnoli, C., Hara, M., Horikawa, Y., Horikawa, Y., Iwamoto, Y., Iwasaki, N., Li, X., Mashima, H., Njølstad, P.R., Ogata, M., Patterson, B., Paz, V.P., Polonsky, K.S., Qaadir, A., So, W.Y., Wang, X., and Ye, H. (1999) Maturity-onset diabetes of the young - a model for genetic studies of diabetes mellitus. In A Common Disease-Genetic and Pathogenetic Aspects of Multifactorial Diseases Edited by Imura, H., Kasuga, M., and Nakao, K., Elsevier Science pp 107-120.

Cox, N.J. (2002) Approaches to identifying genetic variation for complex phenotypes. In Genome Science-Towards a New Paradigm? Edited by H. Yoshikawa, N. Ogasawara, N. Satoh; Elsevier Science BV, Amsterdam, The Netherlands, pp. 241-250.

Invited Speaker – Foreign Meetings, Seminars and Symposia

09/98 Plenary Lecture, 1998 International Genetic Epidemiology Society Meeting, Arcachon, France

11/98 Invited Speaker, New Horizon in the Pathogenesis of Diabetes Mellitus, Kyoto, Japan

04/00 Invited Speaker, Diabetes Conference, Denmark

06/00 Invited Speaker, German Diabetes Meeting, Aachen, Germany

07/00 Invited Speaker, Burroughs Wellcome Trust, Cambridge, England

07/00 Invited Seminar, Steno Diabetes Center, Copenhagen, Denmark

09/00 Visiting Scholar, Japanese Diabetes Society, Tokyo, Japan

09/00 Invited Seminar, Kyoto, Japan

09/00 Invited Seminar, Kobe, Japan

09/00 Invited Seminar, Miyobashi, Japan

11/00 Invited Speaker, Genetics of Complex Disorders, Telethon Italy, Rimini, Italy

07/01 Invited Speaker, Australian Human Genetics Meetings, Cairns, Australia

08/01 Plenary Speaker, International Congress of Schizophrenia Whistler, British Columbia

09/01 Invited Speaker, European Association of Diabetes, Glasgow, Scotland

09/01 Invited Seminar, Section of Endocrinology, Exeter University, Exeter, England

12/01 Invited Speaker, Diabetes Mellitus Meetings, Erice, Italy

04/02 Invited Speaker, Anniversary Symposium, Wurzburg, Germany

04/02 Invited Seminar, Department of Statistical Genetics, Bonn, Germany

05/02 Invited Speaker, Asian Pacific Diabetes Congress, Beijing, China

06/02 Invited Speaker, Uehara Symposium, Tokyo, Japan

09/02 Invited Speaker, Diabetes and Cardiovascular Risk Factors-East Meets West Symposium, Hong Kong, China

10/02 Invited Speaker, SNP Meeting, Reykjavik, Iceland

10/02 Invited Seminar, Shanghai, China

02/03 Invited Speaker, Genomics Bonn, Bonn, Germany

03/03 Invited Speaker, Servier-IGIS Symposia, Cap St. Jean Ferrat, France

04/03 Invited Speaker, Ankylosing Spondilitis Consortium Meeting, Oxford, England

08/03 Invited Speaker, IDF-GD Congress, Lille, France

05/04 Invited Speaker, European Consortium for Type 1 Diabetes, Barcelona, Spain

11/04 Invited Speaker, Samsung International Symposium, Seoul, South Korea

09/05 Invited Speaker, SNP2005 Meeting, Leicestershire, England

Invited Speaker – Domestic Meetings, Seminars and Symposia

12/97 Invited Speaker, Genetic Architecture of Complex Disorders, Baltimore, MD

06/98 Invited Speaker, American Diabetes Association Meetings, Chicago, IL

07/98 Invited Seminar, Department of Human Genetics, The University of Utah, Salt Lake City, UT

10/98 Invited Speaker, 100 th Anniversary of the Joslin Diabetes Center, Boston, MA

03/99 Invited Speaker, NIH Workshop Gene-Environment Interaction, Research Triangle Park, North Carolina

04/99 Invited Seminar, Department of Human Genetics, University of Michigan, Ann Arbor, Michigan

10/99 Invited Seminar, Department of Human Genetics, Yale University, New Haven, CT

10/99 Plenary Speaker, World Psychiatric Genetic Congress, Monterey, CA

11/99 Invited Seminar, Oregon Health Sciences Center, Portland, OR

12/99 Invited Seminar, Southwest Foundation for Biomedical Research, San Antonio, TX

04/00 Invited Seminar, Department of Human Genetics, The University Pittsburgh, Pittsburgh, PA

06/00 Invited Speaker, American Diabetes Association Meetings, San Diego, CA

09/00 Invited Speaker, Newton Morton Celebration, St. Louis, MO

11/00 Invited Seminar, Department of Psychiatry, The University of Virginia, Charlotte, Virginia

01/01 Invited Speaker, NIH Conference Diabetes and Depression, Bethesda, MD

06/01 Invited Speaker, Endocrine Society Meetings, Denver, CO

06/01 Invited Seminar, Department of Psychiatry, University of Colorado, Denver, CO

09/01 Invited Speaker, Hypertension Meetings, Chicago, IL

11/01 Invited Seminar, Department of Human Genetics, UCLA, Los Angeles, CA

04/02 Invited Speaker, NHLBI Consortium Studies, Bethesda, MD

06/02 Invited Seminar, Division of Biostatistical Genetics, The University of Alabama, Birmingham, AL

11/02 Invited Seminar, Biology Department, The University of Miami, Oxford, OH

12/02 Invited Seminar, Biostatistics Department, The University of Wisconsin, Wisconsin

04/03 Invited Speaker, NIH celebration of the 50 th anniversary of Watson and Crick’s discovery of the structure of the DNA double helix—“From Double Helix to Human Sequence and Beyond!”, Bethesda, MD

08/03 Invited Speaker, Gordon Conferences on Human Genetics and Genomics, Colby College-Waterville, Maine

09/03 Invited Speaker, Genome Technology Branch, Bethesda, MD

02/04 Invited Seminar, Dept. of Biology, Oberlin College, Oberlin, OH

03/04 Invited Seminar, University of Arizona, Tuscon, AZ

04/04 Invited Seminar, Dept. of Human Genetics, University of Michigan, Ann Arbor, MI

06/04 Invited Speaker, International Applied Mathematics Society, Nashville, TN

10/04 Invited Speaker, Genetics of Type 2 Diabetes, American Society of Human Genetics Meetings, Toronto, CN

10/04 Invited Speaker, Gene x environment Interaction, American Society of Human Genetics Meetings, Toronto

11/04 Invited Seminar, Dept. of Human Genetics, Emory University, Atlanta, GA

02/05 Invited Speaker, Genetic Epidemiology of Common Diseases: Integrating Genetics, Biology and Medicine,

The 2005 meeting of the Genetic Epidemiology Research Institute (GERI), San Diego, CA

03/05 Invited Speaker, State of the Science in Stuttering Workshop, Washington, D.C.

05/05 Invited Seminar, Wake Forest University

06/05 Invited Speaker, American Diabetes Association Meetings, San Diego, CA

09/05 Invited Scholar, Mayo Clinic, Rochester Minnesota

Send questions and comments to:
Dr. Nicoline Ambrose
Stuttering Research Program
The Department of Speech and Hearing Science
901 S. Sixth St.
Champaign, IL 61820
Phone:217-333-2230